The Interplay of Early Attachment Difficulties and Long-Term Substance Use: A Clinical Case Study
DOI:
https://doi.org/10.55737/trt/v-i.202Keywords:
Substance Induced Psychotic Disorder, Social Withdrawal, Anger, Relapse Prevention, Psychoeducation, Cognitive Behavior TherapyAbstract
The current paper presents the case of a 33-year-old male, who was presented with the psychiatric day program because of constant anger, abusive behavior, social withdrawal, irritability, self-talk, self-laugh, auditory hallucinations, and lack of interest in daily activities. The clinical history showed that patient had substance use disorder, predominantly tobacco, with a current smoking of at least 10 cigarettes daily which had led to repeated and extended psychiatric hospitalization over a period of about 15 years. His clinical picture was in line with DSM-V TR criteria of Substance-Induced Psychotic Disorder with hallucinations being the result of Tobacco Use Disorder which was determined according to the temporal interrelation of substance use and remission of some of the symptoms during supervised abstinence. Mental Status Examination, Behavioral Observation, Clinical Interview and Subjective Symptom Ratings were assessed, along with such formal measures as Positive and Negative Symptom Scale (PANSS), Brief psychiatric Rating Scale (BPRS) and Rotter Incomplete Sentence Blank (RISB), as moderate positive symptoms, significant negative symptoms, and significant general psychopathology with depressive characteristics were observed. The client had auditory hallucinations that expressed early attachments disruption and family relationships. The intervention involved the use of Cognitive Behavioral Therapy (Cognitive Restructuring, Triple Column Technique, Thoughts Create Feelings, Graded Task, Mastery and Pleasure Techniques), Medication Adherence Interventions, Relaxation Techniques, and Psychoeducation of the client and his mother, including the overprotective and overbearing behaviors. After the intervention, the client improved significantly in general functioning, and psychotic symptoms, anger, and withdrawal had decreased.
References
ANF || Anti-Narcotics Force Pakistan. (n.d.). https://www.anf.gov.pk/press_release.php
APA. (2022). Diagnostic and Statistical Manual of Mental Disorders.
Avcı, M. (2025). Adolescents’ experiences with substance use: risks, protective factors and interventions. BMC Psychology, 13(1), 802. https://doi.org/10.1186/s40359-025-03125-w
Beck, A. T. (1976). Cognitive therapy and the emotional disorders. International Universities Press.
Beck, A. T. (1979). Cognitive therapy and the emotional disorders. In Internet Archive. New York : Meridian Book. https://archive.org/details/cognitivetherapy0000beck_e3y7
Beck, A. T., & Haigh, E. A. (2014). Advances in Cognitive Theory and Therapy: The Generic Cognitive Model. Annual Review of Clinical Psychology, 10(1), 1–24. https://doi.org/10.1146/annurev-clinpsy-032813-153734
Beck, J. S. (2011). Cognitive behavior therapy: Basics and beyond, 2nd ed. Book. http://psycnet.apa.org/record/2011-22098-000
Bentall, R. P., De Sousa, P., Varese, F., Wickham, S., Sitko, K., Haarmans, M., & Read, J. (2014). From adversity to psychosis: pathways and mechanisms from specific adversities to specific symptoms. Social Psychiatry and Psychiatric Epidemiology, 49(7), 1011–1022. https://doi.org/10.1007/s00127-014-0914-0
Bernstein, D. A., Borkovec, T. D., & Hazlett-Stevens, H. (2000). New directions in progressive relaxation training: A guidebook for helping professionals. Praeger.
Bowlby, J. (1982). Attachment and loss: Vol. 1. Attachment; Vol. 3. Loss (2nd ed.). Basic Books.
Chadwick, P., Birchwood, M. J., & Trower, P. (1996). Cognitive therapy for delusions, voices and paranoia. John Wiley & Sons.
Flinn, A., Hefferman-Clarke, R., Parker, S., Allsopp, K., Zhou, L., Begemann, M., Bentall, R., & Varese, F. (2025). Cumulative exposure to childhood adversity and risk of adult psychosis: a dose–response meta-analysis. Psychological Medicine, 55, e162. https://doi.org/10.1017/s0033291725001138
Garety, P. A., Kuipers, E., Fowler, D., Freeman, D., & Bebbington, P. E. (2001). A cognitive model of the positive symptoms of psychosis. Psychological Medicine, 31(2), 189–195. https://doi.org/10.1017/s0033291701003312
Gross, J. J. (2015). Emotion Regulation: Current status and future Prospects. Psychological Inquiry, 26(1), 1–26. https://doi.org/10.1080/1047840x.2014.940781
Gurillo, P., Jauhar, S., Murray, R. M., & MacCabe, J. H. (2015). Does tobacco use cause psychosis? Systematic review and meta-analysis. The Lancet Psychiatry, 2(8), 718–725. https://doi.org/10.1016/s2215-0366(15)00152-2
Han, B., Aung, T. W., Volkow, N. D., Silveira, M. L., Kimmel, H. L., Blanco, C., & Compton, W. M. (2023). Tobacco use, nicotine dependence, and cessation methods in US adults with psychosis. JAMA Network Open, 6(3), e234995. https://doi.org/10.1001/jamanetworkopen.2023.4995
Hofmann, S. G., Asnaani, A., Vonk, I. J. J., Sawyer, A. T., & Fang, A. (2012). The Efficacy of Cognitive Behavioral therapy: A review of Meta-analyses. Cognitive Therapy and Research, 36(5), 427–440. https://doi.org/10.1007/s10608-012-9476-1
Hogue, A., Becker, S. J., Wenzel, K., Henderson, C. E., Bobek, M., Levy, S., & Fishman, M. (2021). Family involvement in treatment and recovery for substance use disorders among transition-age youth: Research bedrocks and opportunities. Journal of Substance Abuse Treatment, 129, 108402. https://doi.org/10.1016/j.jsat.2021.108402
Hunter, A., Murray, R., Asher, L., & Leonardi-Bee, J. (2018). The effects of tobacco smoking, and prenatal tobacco smoke exposure, on risk of schizophrenia: A Systematic Review and Meta-Analysis. Nicotine & Tobacco Research, 22(1), 3–10. https://doi.org/10.1093/ntr/nty160
Jacobson, E. (1938). Progressive relaxation. University of Chicago Press.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987). The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13(2), 261–276. https://doi.org/10.1093/schbul/13.2.261
Kemp, R., Hayward, P., Applewhaite, G., Everitt, B., & David, A. (1996). Compliance therapy in psychotic patients: randomised controlled trial. BMJ, 312(7027), 345–349. https://doi.org/10.1136/bmj.312.7027.345
Ma, K. (2006). Attachment theory in adult psychiatry. Part 1: Conceptualisations, measurement and clinical research findings. Advances in Psychiatric Treatment, 12(6), 440–449. https://doi.org/10.1192/apt.12.6.440
McCrory, E., De Brito, S. A., & Viding, E. (2011). The Impact of Childhood Maltreatment: A review of neurobiological and genetic factors. Frontiers in Psychiatry, 2, 48. https://doi.org/10.3389/fpsyt.2011.00048
Migalova, E., Furstova, J., Hasto, J., Tavel, P., & Kascakova, N. (2025). The link of adverse childhood experiences and attachment to maladaptive personality traits in adults diagnosed with substance use disorder. BMC Psychology, 13(1), 974. https://doi.org/10.1186/s40359-025-03331-6
Miller, W. R., & Rollnick, S. (2013). Motivational interviewing: helping people change.
Morrison, A. P., Hutton, P., Wardle, M., Spencer, H., Barratt, S., Brabban, A., Callcott, P., Christodoulides, T., Dudley, R., French, P., Lumley, V., Tai, S. J., & Turkington, D. (2011). Cognitive therapy for people with a schizophrenia spectrum diagnosis not taking antipsychotic medication: an exploratory trial. Psychological Medicine, 42(5), 1049–1056. https://doi.org/10.1017/s0033291711001899
Mueser, K. T., Noordsy, D. L., Drake, R. E., Fox, L., & Barlow, D. H. (2003). Integrated Treatment for Dual Disorders: A Guide to Effective practice.
Mustonen, A., Niemelä, S., McGrath, J. J., Murray, G. K., Nordström, T., Mäki, P., Miettunen, J., & Scott, J. G. (2018). Adolescent inhalant use and psychosis risk – a prospective longitudinal study. Schizophrenia Research, 201, 360–366. https://doi.org/10.1016/j.schres.2018.05.013
Overall, J. E., & Gorham, D. R. (1962). The brief Psychiatric rating scale. Psychological Reports, 10(3), 799–812. https://doi.org/10.2466/pr0.1962.10.3.799
Padesky, C. A., & Mooney, K. A. (2012). Strengths‐Based Cognitive–Behavioural therapy: A Four‐Step model to build resilience. Clinical Psychology & Psychotherapy, 19(4), 283–290. https://doi.org/10.1002/cpp.1795
Parker, G. (1983). Parental overprotection: A risk factor in psychosocial development. Grune & Stratton.
Persons, J. B. (1989). Cognitive Therapy in Practice: A Case Formulation approach.
Psychosis risk is 2-3 times greater in those with major childhood adversities, study Finds | Brain & Behavior Research Foundation. (2025, July 10). Bbrfoundation. https://bbrfoundation.org/content/psychosis-risk-2-3-times-greater-those-major-childhood-adversities-study-finds
Quigley, H., & MacCabe, J. H. (2019). The relationship between nicotine and psychosis. Therapeutic Advances in Psychopharmacology, 9, 2045125319859969. https://doi.org/10.1177/2045125319859969
Read, J., Fosse, R., Moskowitz, A., & Perry, B. (2014). The traumagenic neurodevelopmental model of psychosis revisited. Neuropsychiatry, 4(1), 65–79. https://doi.org/10.2217/npy.13.89
Read, J., Van Os, J., Morrison, A. P., & Ross, C. A. (2005). Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications. Acta Psychiatrica Scandinavica, 112(5), 330–350. https://doi.org/10.1111/j.1600-0447.2005.00634.x
Ricci, V., Martinotti, G., & Maina, G. (2024). Substance-Induced Psychosis: diagnostic challenges and phenomenological insights. Psychiatry International, 5(4), 759–772. https://doi.org/10.3390/psychiatryint5040052
Schindler, A. (2019). Attachment and Substance Use Disorders—Theoretical models, Empirical evidence, and Implications for Treatment. Frontiers in Psychiatry, 10, 727. https://doi.org/10.3389/fpsyt.2019.00727
Schindler, A., Thomasius, R., Sack, P., Gemeinhardt, B., KÜStner, U., & Eckert, J. (2005). Attachment and substance use disorders: A review of the literature and a study in drug dependent adolescents. Attachment & Human Development, 7(3), 207–228. https://doi.org/10.1080/14616730500173918
Umar, M., Mustajab, M., Fatima, Z., Richard, R. M., Qureshi, S. R., Muneer, S. U., Shamim, L., Ahmed, S., Hashim, H. T., & Basalilah, A. F. M. (2025). The impact of adverse childhood experiences in the development of post-traumatic stress disorder in adults over 18 years of age: a systematic review. BMC Psychiatry, 25(1), 759. https://doi.org/10.1186/s12888-025-07090-x
Varese, F., Smeets, F., Drukker, M., Lieverse, R., Lataster, T., Viechtbauer, W., Read, J., Van Os, J., & Bentall, R. P. (2012). Childhood adversities Increase the risk of Psychosis: A Meta-analysis of Patient-Control, Prospective- and Cross-sectional Cohort Studies. Schizophrenia Bulletin, 38(4), 661–671. https://doi.org/10.1093/schbul/sbs050
World Health Organization. (2015). Global Adult Tobacco Survey (GATS) Pakistan 2014: Executive summary [PDF]. World Health Organization.
Xi, C., Xu, X., & Wang, S. (2025). Predicting psychotic-like experiences among adolescents: the interplay of childhood trauma, cognitive biases, neuroticism, and depression. Child and Adolescent Psychiatry and Mental Health, 19(1), 20. https://doi.org/10.1186/s13034-025-00878-5
Yao, B., Hall, M., Tusuzian, E., Cohen, B., Öngür, D., & Chouinard, V. (2025). Childhood adverse events and their association with psychotic symptoms and quality of life in young adults with first episode psychosis and unaffected siblings. Schizophrenia Research, 283, 137–143. https://doi.org/10.1016/j.schres.2025.07.006
Young, J. E., Klosko, J. S., & Weishaar, M. E. (2003). Schema therapy: A practitioner’s guide. Guilford Press.
Zubin, J., & Spring, B. (1977). Vulnerability: A new view of schizophrenia. Journal of Abnormal Psychology, 86(2), 103–126. https://doi.org/10.1037/0021-843x.86.2.103
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.


